Levels of Vitamin D and their Association with Complications of Type 2 Diabetes Mellituss Pages 17-23

Sukhraj Kaur1 and Pashaura Singh Sandhu2

1Department of Biochemistry, Government Medical College, Amritsar, India; 2Department of Medicine, Government Medical College, Amritsar, India

DOI: https://doi.org/10.12970/2310-9971.2019.07.03

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Abstract: Introduction: Type 2 diabetes mellitus is a non communicable disorder associated with hyperglycemia. It is associated with various micro and macro vascular complications. Vitamin D a stercosterol is an important molecule associated with many skeletal and extra skeletal functions in the body. Vitamin D maintains glucose homeostasis and has an important role to play in manifestations of various complications.
Material and Method: The present study comprised of one hundred patients of diabetic complications compared with one hundred normal individuals. All the subjects were investigated for blood glucose, Glycated haemoglobin, lipid profile and vitamin D
Results: Glycemic control and lipid profile was deranged in patients with complications of type 2 diabetes mellitus. Levels of vitamin D were significantly decreased in patients as compared to controls. Moreover 73% of the patients were deficient in vitamin D.
Conclusions: Vitamin D acts through various non skeletal pathways and helps to regulate glucose. In the current study it showed negative correlation with Glycated Haemoglobin, Triglycerides and Cholesterol thus indicating that maintaining vitamin D levels can delay the onset of diabetic complications.

Keywords: Diabetic complications, Vitamin D, glycemic control. Read more