Clinicopathological Determinants of Treatment Outcomes of Nasal Polyps in a Black African Cohort Pages 17-21

Adekunle Adeyemo1, Temilola O. Owojuyigbe2, Ajibola T. Osukoya3, Akumbu S. Ohuche3, Ogochukwu C. Ejiofor3 and Y.B. Amusa1

1Department of Otorhinolaryngology, Obafemi Awolowo University, Ile Ife, Nigeria; 2Department of Haematology and Immunology, Obafemi Awolowo University, Ile Ife, Nigeria; 3Department of Otorhinolaryngology Obafemi Awolowo University Teaching Hospital Ile Ife, Nigeria

DOI: https://doi.org/10.12970/2308-7978.2019.07.04

Download PDF

Abstract: Background: The propensity for nasal polyps to recur post treatment is a subject of ongoing research globally. There are however no studies focusing on determinants of post treatment recurrence of polyps in a predominantly black population.
Methodology: This was a retrospective review of clinical notes and charts of all black patients managed for nasal polyps in our centre during the study period.

Result: Forty-four patients with median age of 27.50 years (IQR = 22.75) were studied. There were 21 males and 23 females. Forty-two patients (94.46%) had an initial medical treatment while two patients presenting with recurrent disease were managed surgically from the onset. Twenty two (52.38%) of patients who had an initial medical treatment had complete disease resolution with no recurrence while 20 (47.62%) patients had persistent disease after one month of medical treatment and were offered surgery. Of the 21 patients who had surgery, 8 patients each had either simple polypectomy or combination of simple polypectomy and antrostomy. The rest (5) had Functional endoscopic sinus surgery. There was no significant difference in outcomes between the different surgical groups with a cumulative post-surgery recurrence rate of 23.81%; however, the addition of antrostomy increased the rate of post-operative adhesions. There was no significant difference in the age, sex, duration of symptoms and treatment modality among patients with respect to recurrence.

Conclusion: Nasal polyps recur post treatment in an unpredictable manner, initial medical management is efficacious in eliminating nasal polyps in more than half of the patients potentially avoiding surgeries in such patients.

Keywords: Nasal polyps, antrostomy, Functional Endoscopic Sinus Surgery, FESS, simple polypectomy. Read more →