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Synthesis of Biologically Active α-Aminophosphonates Pages 49-60
Gandavaram Syam Prasada and Gollapalli Nageswara Raob
aDepartment of Chemistry, Gayatri Degree & PG College, Tirupati, 517501, India; bSchool of Chemistry, Andhra University, Visakhapatnam, 530003, India
DOI: http://dx.doi.org/10.12970/2308-8044.2013.01.01.5
Download PDFAbstract: Highly convergent Synthesis of α-aminophosphonates were most conveniently achieved using organophosphorus chemistry. Synthesis of α-aminophosphonates were accomplished by three-component coupling of carbonyl, amine and hydrophosphoryl compounds. These aminophosphonates exhibited promising antimicrobial, antioxidant and anticancer activity. Some recent developments and applications to the synthesis of biologically active α-aminophosphonates are also included.
Keywords: α-Aminophosphonates, antimicrobial activity, antioxidant activity, anticancer activity. Read more