Tuberculosis and Diabetes: About 260 Cases (Pages 47-52)

 

Hayat Ahandar*, Nassime Essabah Haraj, Siham El Aziz and Asmaa Chadli

Department of Endocrinology, Diabetology and Metabolic Diseases, CHU Ibn Rochd, Casablanca, Morocco
 
DOI: http://dx.doi.org/10.12970/2310-9971.2015.03.02.4

Abstract: The diabetes (DT) is associated with a greater risk of developing an infectious disease. Thus the association between diabetes and tuberculosis (TBK) is well-known. We conducted a cohort study of a random sample of 260 TBK patients diagnosed and supervised in 3 tuberculosis centers and respiratory diseases (CDTMR) in Casablanca, between February and September 2014, which aimed to specify the prevalence of diabetes among TBK patients, and describe the clinical and evolutionary characteristics of this association.

Patients and Methods: The diabetes screening of all the patients was performed using a capillary glycémie (CG), if the rate of glycerin on an empty stomach is ≥1 .26 g/l or at any time of day≥ 2 g/l, an A1C test was performed, so it was considered diabetic, any patient who has been already known as diabetic or having a HbA1c≥ 6.5%. Variables such as the type of TBK, the clinical and radiological characteristics were collected and analyzed (Epi Info).

Results: The prevalence of the diabetes was about 36% (94), 64% are known as diabetics and 36% are recently diagnosed. The domination was male with an average age of 50 ± 14.97. Radiologically, the basic damage and diffuse lesions were significantly associated with the existence of a diabetes compared to non-diabetic patients (p = 0.0001). Regarding the therapeutic results, we detected a higher relapse rate (21%, p=0.01), a failure rate of 12% (p = 0.01) and 7% of resistance (P: 0.02). Health-giving was significantly associated with non-diabetic persons (TND)(P <0.0001).

Conclusion: We noticed a high prevalence of diabetes among TBK patients. The diabetic patients have most severe forms of tuberculosis; atypical locations and often widespread radiological abnormalities often extended.

Keywords: Diabetes mellitus, Tuberculosis, Casablanca, Prevalence, association characteristics.
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