Lipid Levels and Associated Cardiovascular Risk Factors in Moroccan Type 2 Diabetes: A Case Control Study (EPIDIAM Study) Pages 1-7

Youness El Achhab1,2, Mohamed Berraho1, Driss Salah3, Chakib Nejjari1 and Mohamed Chikri4

1Laboratory of Epidemiology, Clinical Research and Community Health, Medicine Faculty of Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco; 2Regional Centre for Careers Education and Training (CRMEF), Taza, Morocco; 3Faculty of Science, Mohammed V University, Agdal, Rabat, Morocco; 4Laboratory of Biochemistry and Molecular Biology, Medicine Faculty of Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco

DOI: http://dx.doi.org/10.12970/2310-9971.2014.02.01.1

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Abstract: Background: The management of diabetic dyslipidaemia, a well-recognized and modifiable risk factor, is a key element in the multifactorial approach to prevent cardiovascular diseases (CVD) in individuals with type 2 diabetes (T2DM).

Objective: The aim of this study is to describe lipids profile and to compare CVD risk factors in Moroccan individuals with and without T2DM.

Subjects and Methods: The study population consisted of 1307 unrelated T2D and 984 non-diabetics subjects. This was a case control study carried out in urban and rural primary health care centers. The survey was conducted from January 2006 to July 2008.

Results: This case control study performed in a group of type 2 diabetic patients (1307) and non-diabetic (984) adults’ shows that T2D is strongly and independently associated with CVD risk factors, which are, hypertension (OR 4.06, 95% CI: 3.35-4.93, p <0.001), elevated TGs (OR 1.77, CI: 1.45-2.18, p <0.001), central obesity (OR 1.67, CI: 1.30-2.16, p <0.001), been female (OR 0.79, CI: 0.64-0.97, p =0.022), and been older-age (p =0.001). Strong prevalence of CVD risk factors has also shown among non-diabetics.

Conclusion: The present study has found a high prevalence of CVD risk factors among T2D patients and controls despite the significant difference between them.

Keywords: Type 2 Diabetes Mellitus, Dyslipidaemia, Cardiovascular disease, Risk factors, Morocco. Read more