
HBsAg Serconversion is Important but not Sufficient for Clearance of HBV Infection –A Time To Re-Think: A Case Report & Review of Literature Pages 4-6
Fazal Karim1, Mamun Al-Mahtab2 and Salimur Rahman2
1Department of Hepatology, Sir Salimullah Medical College Mitford Hospital, Dhaka, Bangladesh; 2Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
http://dx.doi.org/10.12970/2308-6483.2015.03.01.2
Abstract: Hepatitis B viral infection is a worldwide problem. About 95% adult recovers from acute infection naturally. Anti HBs is a marker of recovery from acute hepatitis B. Anti HBs is a usually consistent with decline of cccDNA in hepatocytes. However there may be situations where viral rebound occurs due to persistence of cccDNA. This case report depicts such a picture. Measurement of cccDNA is perhaps essential before cure from hepatitis B infection can be declared.
Keywords: cccDNA, HBsAg, Anti HBs, HBV, NA. Read more