https://synergypublishers.com/pms/index.php/jedm <h3>Journal of Endocrinology and Diabetes Mellitus (JEDM) has ceased publication and is no longer accepting submissions.</h3> <h3>All previously published articles are available in the archive of the journal.</h3> Synergy Publishers en-US Journal of Endocrinology and Diabetes Mellitus 2310-9971 https://synergypublishers.com/pms/index.php/jedm/article/view/1567 This study aimed to analyze the effects of high-load (HL) resistance exercise (RE), low-load (LL) RE, and LL RE with blood flow restriction (LL + BFR) in peripheral oxygen saturation level (SpO2), heart rate (HR), and double product (DP: HR × systolic blood pressure [SBP]) in untrained women with type 2 diabetes (T2DM). Ten untrained women with T2DM (Age = 56.9 ± 7.4 years; BMI = 27.2 ± 4.2 kg/m2; and Diagnostic time = 10.6 ± 4.1 years) participated in this study. Participants attended a local gym for four non-consecutive days. During the first visit, arterial occlusion pressure (AOP) and predictive values of one maximum repetition (1RM) for knee extension exercise (KE) were assessed. The second, third, and fourth visits were randomly assigned to the following: HL RE (~65% of predicted 1RM in 3 sets of 10 repetitions), LL RE (~20% of predicted 1RM in 3 sets of 15 repetitions), and LL + BFR RE (~20% of predicted 1RM in 3 sets of 15 repetitions; 50% of AOP). HR, SBP e SpO2 were assessed before and immediately after each protocol. All protocols significantly increased the analyzed variables (p ≤ 0.05). There were no significant differences in hemodynamic responses between the protocols (p > 0.05). Therefore, resistance exercise with BFR seems to promote cardiovascular responses similar to traditional low and high load resistance exercise protocols in untrained diabetic women. Marina Gonçalves Assis Nailton José Brandão de Albuquerque Filho Arthur Wagner da Silva Rodrigues Ana Beatriz Alves Martins Victor Sabino de Queiros Eliete Samara Batista dos Santos Jefferson da Silva Novaes Gabriel Rodrigues Neto Copyright (c) 2021-02-11 2021-02-11 9 1 1 6 10.12970/2310-9971.2021.09.01