Diabetic Mastopathy: A Rare Complication of Type 1 Diabetes
DOI:
https://doi.org/10.12970/2310-9971.2015.03.01.2Keywords:
Breast disease, mastopathy, diabetes, insulin, histology.Abstract
Diabetic mastopathy is a rare complication encountered in type I diabetes. This observation relates diagnostic, morphological, therapeutic and evolutionary characteristics of diabetic mastopathy. Our case consist of a young woman aged 30 years, type 1 diabetic for 20 years with chronic blood sugar imbalance (HBA1C 13%); at the stage of microvascular complications. During the last year, she has had a painless bilateral breast induration, while physical examination found very hard breasts without inflammatory signs or well-individualized nodule. The echo-mammography showed a heterogeneous appearance of the two breasts with a nodule in the upper inner quadrant of the left breast rated ACR4 at the BI-RADS classification. The surgical biopsy showed dense fibrous tissue with a chronic inflammatory infiltrate, predominately lymphocytic, related to diabetic mastopathy. Abstention and monitoring were recommended. Indeed, clinical and radiological signs of diabetic mastopathy are nonspecific and can leave a suspected breast cancer. The pathogenesis is not known. The duration of diabetes and hyperglycemia could be contributing factors. After histological diagnosis, in agreement with the clinic (old and complicated diabetes), surgical abstention is the rule.References
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