Diabetic Patients’ Metabolic Profile During Ramadan
DOI:
https://doi.org/10.12970/2310-9971.2020.08.01Keywords:
Diabetes, metabolic parameters, therapeutic education, Ramadan fasting.Abstract
Background: Fasting during the month of Ramadan is a religious obligation. The objective of our work was to assess the impact of Ramadan fasting on type 2 diabetes metabolic parameters. Patients and Methods: Prospective study including 160 diabetic patients from May to July 2018. Results: We have found a sex ratio M/F of 0.7, a mean age 53.54±11.22 years. A low educational 43.1% and family life 81.3% of patients. The average diabetes duration was 10±8 years, with irregular follow-up in 10.6%. Mean BMI was 32.4±8 kg/m². 68.8% of patients had observed fasting. Patients were treated with oral antidiabetic drugs only in 63.1%, bed-time insulin combination 25%, insulin therapy alone 9.4% and diet alone 2.5%. The frequency hypoglycemia 25% and 28% of hyperglycemia were observed in the youngest’s group (p=0.5). The mean energy intake was 1754.31±433.3 Kcal and a mean weight loss of 2.3±1.16 kg was observed during Ramadan. A significant decreased was found for fasting blood glucose (1.36±0.4 vs 1.46±0.46g/l), HbA1c (7.5±1.28 vs 7.93±1.84%), blood pressure (12±1.06 vs 13±1.49 cmHg), levels of LDL-C (0.86±0.27 vs 1.12±0.45 g/L), TC (1.66±0.5 vs 1.8±1.23 g/L) and uricemia (51.6±20 vs 56.4±21 mg/L) with stabilization of TG (1.39±0.75 vs 1.38±0.69 g/L) (p <0.001), and increased HDL-C (0.66±0.3 vs 0.6±0.41g/L). In contrast, albuminemia (50.4±19.5 vs. 48.9±14.7 g/l), creatinine (11.1±2.2 vs. 9.12±3.7mg/l) had increased (p=0.005). Conclusion: These data suggest that fasting may be particularly beneficial for people with diabetes as a nutritional and glycemic intervention. However, these effects are transient, given the short duration of the fasting period.References
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