Adventitial (Erzengin’s) Atherosclerocalcification: Surprise Location and a New Concept of the Formation of Atherosclero-calcifications in 2013. The Tip of the İceberg and a New İnnovative Current Drugs for Certain Solution with the Erzengin’s Polypill

Authors

  • Faruk Erzengin Department of Cardiology, Faculty of Medicine, University of Istanbul, Çapa, Istanbul, Turkey

DOI:

https://doi.org/10.12970/2311-052X.2013.01.02.2

Keywords:

 Adventitial (Erzengin’s) atherosclerocalcification, Formation of atherosclerocalcific plaques on the adventitia, Multi Slice Computed Tomographic Angiography, Innovative medical treatment of coronary atherosclerosis, Erzengin’s Polypill.

Abstract

Formation of atherosclerotic and calcified plaque begins and grows up not only beneath the endothelium (intimae), but also in the adventitial subepithelium on the coronary arteries.

A new innovative combined drug (polypill) is certainly releases, regress and prevents of formation of the atherosclerotic and calcified plaque of arteries.

References

Fuster V. Epidemic of cardiovascular disease and stroke: The three main challenges. Circulation 1999; 99: 1132-7. http://dx.doi.org/10.1161/01.CIR.99.9.1132

Fuster V. Atherosclerosis, thrombosis, and vascular biology. Cecil Textbook of Medicine, Ed: Lee Goldman, Dennis Ausiello, 22nd Edition, Saunders, Philadelphia, Philadelphia 2004; pp. 383-400.

Lipid Study Group. Prevention of cardiovascular events and death with pravastatin in patient with coronary heart disease and abroad range of initial cholesterol levels. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. N Eng J Med 1998; 339: 1349. http://dx.doi.org/10.1056/NEJM199811053391902

Falk E, Fuster V. Atherogenesis and its determinants. Hurst’s The Heart, Ed: Valentin Fuster, R. Wayne Alexander, Robert A. O’Rourke, Robert Roberts, Spencer B. King III, Hein J.J.Wellens. 10th edition, McGraw-Hıll, New York 2001; Vol. 1: pp. 1065-1093.

Ross R. The biology of atherosclerosis. In: Topol E J, ed. Comprehensive Cardiovascular Medicine. Philadelphia: lippincott-Raven 1998; 13.

Iiyama K, Hajra L, Iiyama M, Li H. Patterns of vascular cell adhesion molecule-1 and intracellula adhesion molecule-1 expression in rabbit and Mouse atherosclerotic lesions and at site predisposed to lesion formation. Circ Res 1999; 85: 199-207. http://dx.doi.org/10.1161/01.RES.85.2.199

Lesckha S, Alkadhi H, Plass A, et al. Accuracy of MSCT coronary angiography with 64-slice technology: First experience. Eur Heart J 2005; 26: 1482-7. http://dx.doi.org/10.1093/eurheartj/ehi261

Erzengin F, Büyüköztürk K. Cardiac Imaging in Textbook of Internal Medicine, Ed: Kemalettin Büyüköztürk, Faruk Erzengin et al. Nobel Istanbul, 2007; pp. 1623-44.

de Ruijter W, Westendorp RG, Assendelft WJ, Elzen WP, Cessie S, Gussekloo J. Use of Framinggham risk and new biomarkers to predict cardiovascular mortality in older people: Population base observational cohort study. BMJ 2009; 338: a3083. http://dx.doi.org/10.1136/bmj.a3083

Third Report of the National Cholesterol Educatio Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adult (Adult Treatment Panel III) final report. Circulation 2002; 106: 3143-21.

Conroy RM, Pyorala K, Fitzgerald AP, Sans S, Menoti A, De Backer G. Estimation of ten year risk of fatal cardiovascular disease in Europe: The SCORE Project. Eur Heart J 2003; 290: 898-904.

Hendel RC, Patel MR, Kramer CM, Poon M. ACC/ACR/SCMR/ASNC /NASCI/ SCAI/SIR Appropriateness Criteria for Cardiac Computed Tomography and Cardiac Magnetic Resonance Imaging. J Am Coll Cardiol 2006; 48: 1-23.

Achenbach S, Daniel WG. Computed Tomography of the Heart. Braunwald’s Heart Disease,7th edition, Elsevier Saunders, Pensilvania, USA 2005; 285-7.

Higgins CB, de Roos A. MRI and CT of the Cardiovascular system. Lipincor & Williams and Wilkins, USA and the Netherlands 2006.

Achenbach S, Moselewski F, Ropers D, et al. Detection of calcified and noncalcified coronary atherosclerotic plaque by contrast-enhanced, submillimeter multidetector spiral computed tomography: a segment-based comparison with intravscular ultrasound. Circulation 2004; 109: 14-7. http://dx.doi.org/10.1161/01.CIR.0000111517.69230.0F

Sangiorgy G, Rumberg JA, Severson A, et al. Arterial calcification and not lümen stenosis is highly corra, elated with atherosclerotic plaque burden in humans: A histologic study of 723 coronary artery segments using non decalcifying methodology. J Am Coll Cardiol 1998; 31: 126-33. http://dx.doi.org/10.1016/S0735-1097(97)00443-9

Mintz GS, Pichard AD, Pompa JJ, et al. Determinants and correlates of target lesions calcium in coronary artery disease: A clinicali angiographic and intravascular ultasound study. J Am Coll Cardiol 1997; 29: 268-74. http://dx.doi.org/10.1016/S0735-1097(96)00479-2

Yönal İ, Banzagch M, Özcan M, Adalet K, Erzengin F. Cardiac computed tomography; the unique noninvasive method for the detection of coronary atherosclerotic plaque morphology and for the diagnosis of silent ischemia, lumen narrowing calcification of adventitia: with two case reports. The Heart Surgery Forum. A Cardiothoracic Multymedia J 2009; 12: 69-70.

Erzengin F. Adventitial Calcification: Surprise Location. Atherosclerotic and calcified plaques begin and grow up not only beneath the endothelium, but also on the adventitia. 78th European Atherosclerosis Society Congress (78th EAS Congress), Hamburg, Germany June 20-23, 2010.

Erzengin F. Adventitial (Erzengin’s) Atherosclrero-calcification: Surprise Location. Atherosclerotic and calcified plaques begin and grow up not only beneath the endothelium, but also on the adventitia. THE 3th WORLD MEDICINE CONGRESS, Abstract book, NALCHIK-RUSSIA September 20-23, 2010; p. 4.

Erzengin F. Adventitial arherosclerocalcifications: A new surprise location, In Abstract book, 7th Congress of update in Cardiology and Cardiovascular Surgery in association with TCT Mediterranean, ANTALYA-TURKEY 24-27th March, 2011.

Bissen EA. Plaque Adventitia: Service Hatch or Battleground? 79th EAS Congress Gothenburg, Sweden, June 26-29, 2011.

Erzengin F. ERZENGİN’S POLYPILL: An additional medical treatment of the atherosclerocalcifications. The 4th international medical conference on ‘‘advances incontemporary medicine’’ ISTANBUL 7-8 October, 2011.

Erzengin F: Letter to the editor: Adventıtıal atherosclerosıs and calcıfıcatıons: Cardiovascular Sciences, Accepted for press (07.06.2010- Nm: 18915).

Erzengin F. Erzengin’s Polypill: an additional and new medical treatment of atherosclerocalcifications. Int J Cardiol 2012; 147: 111-2. http://dx.doi.org/10.1016/S0167-5273(12)70270-X

Iacobellis G, Ribaudo MC, Zappaterrano A, Iannucci CV, Leonetti F. Relation betweenepicardial adipose tissue and left ventricular mass. Am J Cardiol 2004; 94: 1084-7. http://dx.doi.org/10.1016/j.amjcard.2004.06.075

Downloads

Published

2013-07-02

Issue

Section

Articles