Opinion: Presumable Reason of Interrelationship between Autoimmune Hemolytic Anemia and Cancer Arising
DOI:
https://doi.org/10.12970/2310-9874.2015.03.01.2Keywords:
Hemolytic anemia, immunocompetent cells, organic and inorganic hemolytic toxinsAbstract
The mechanism of malignant transformation in autoimmune hemolytic anemia can be based on the inclusion of immunocompetent cells in different cellular cooperations. Antibodies and T-cytotoxic cells can induce perforations of different degree on somatic cells plasma membranes. Total negative charge of plasma membranes decrease, and the cells acquire the capability of closely approaching, which frequently, especially upon coincidence of the perforated parts, may serve as a prerequisite to fusion process and formation of cancerous cell.
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