Association of Lymphocytic Thyroiditis and Thyroid Papillary Cancer
DOI:
https://doi.org/10.12970/2310-9874.2015.03.03.2Keywords:
Lymphocytic thyroiditis, papillary carcinoma, thyroid, autoimmunity, Thyroid NeoplasmsAbstract
Introduction: The association between the papillary thyroid carcinoma (PTC) and the lymphocytic thyroiditis (LT) is common and remains controversial.
Objectives: Define the prevalence of the association of LT with PTC and the characteristics of patients who suffer from PTC with LT compared to those without LT.
Methods: This is a retrospective cross-sectional study of patients followed for PTC within the Department of Endocrinology of Casablanca between 1986 and 2015. The statistical analysis was performed using SPSS 16.
Results: Among 348 files of patients who suffer from PTC, 49 patients had associated LT, giving a frequency of about 14.1%. The patients were divided into two groups: group with PTC + LT and group with PTC without LT. A female predominance was noticed in both groups. The tumor size was lower in the group with PTC + LT: 0.6cm vs 1.4cm in patients without LT (p = 0.001). TNM1 class was predominant in the LT group (p = 0.004). There was no difference in recurrence rates in both groups.
Conclusions: The association of PTC with LT is common; patients with LT typically present with smaller tumor size and lower TNM stage and have a generally good prognosis.
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