Bariatric Surgery and its Place in Modern Diabetology

Dan Mircea Cheța, Vlad Horia Chirilă

Abstract


This short presentation includes recent international information. Obesity became a very difficult problem of the public health in the last decades. Bariatric surgery seems useful in appropiately selected patients. It determines an important weight loss in obese patients with type 1 diabetes and an improve in their insulin requirements and glycemic status. Obesity is associated with low-grade inflammation of the adipose tissue, insulin-resistance and type 2 diabetes mellitus. The remission of type 2 diabetes may be achieved after bariatric surgery, but rates vary according to subjects’ baseline characteristics. Although the mechanisms underlying the efficacy of bariatric surgery are not totally clear, gastrointestinal and pancreatic peptides are considered to play an important role. The landscape of bariatric surgery rapidly evolved in the past few years. Recently, bile acids emerged as an important factor for explaining the benefits of bariatric surgery and its perspectives.


Keywords


Bariatric/metabolic surgery, obesity, sleeve gastrectomy, type 1 diabetes mellitus, type 2 diabetes mellitus, weight loss.

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