Efficacy of Essential Oils in In Vitro Control of Acinetobacter baumannii Pages 11-22
Glaucimeire Rodrigues de Andrade1, Dora Inês Kozusny-Andreani2, Roberto Andreani Junior2, Igor Renan Honorato Gatto3 and Rogério Rodrigo Ramos4
1Universidade Federal de Uberlândia, MG, Brazil; 2Department of Microbiology and Postgraduate Program in Environmental Sciences, Universidade Brasil, Fernandópolis, SP, Brazil; 3Ourofino Animal Health Ltda, Cravinhos, SP, Brazil; 4Universidade Brasil, Fernandópolis, SP, Brazil
DOI: https://doi.org/10.12970/2311-1755.2020.08.03
Download PDFAbstract: Although Acinetobacter baumannii is common in nature and considered human skin and respiratory tract commensal, it has also been associated to serious infectious diseases, such as pneumonia, urinary tract infection, endocarditis, wound infection, meningitis and septicemia. The present study aimed to evaluate the intrinsic antimicrobial activity of essential oils on the Acinetobacter baumannii ATCC 17978 strain. We used essential oil of rosemary, artemisia, cinnamon, camphor, citronella, Indian clove, Eucalyptus globulus, Eucalyptus staigeriana, Eucalyptus citriodora, tea tree (also known as melaleuca), mint, oregano and sage, in concentrations that ranged from 0 to 100%. The antibacterial activity was determined through the broth microdilution method and through bactericidal kinetics of essential oils. All the oils performed antibacterial activity against Acinetobacter baumannii. citronella, Eucalyptus staigeriana and mint oils presented lower minimum inhibitory concentration and minimum bactericidal concentration. Oregano, tea tree and Indian clove oils presented higher bacterial death rate, and they canceled the microbial load of A. baumannii in up to 60 minutes.
Keywords: Medicinal plants, Essential compounds for treatment, Antimicrobials, Mechanisms of action, Acinetobacter baumannii, Infectious diseases.
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