Buruli Ulcer: A Review (GJDVv2n2a5) - synergy - synergy

Buruli Ulcer: A Review Pages 69-75

Kimberly F. Faldettaa, Michael A. Santosa, Joanne E. Smuckerb, Scott A. Nortonc and Andrea L. Zaengleina,b,d

aPenn State University, College of Medicine, Global Health Scholars Program, Hershey, PA, USA; bDepartment of Dermatology, Penn State/ Hershey Medical Center, Hershey, PA, USA; cDepartment of Dermatology, Children’s National Medical Center, Washington DC, USA; dDepartment of Pediatrics, Penn State/ Hershey Medical Center, Hershey, PA, USA

DOI: http://dx.doi.org/10.12970/2310-998X.2014.02.02.5

Abstract: Buruli ulcer (BU) is a severe necrotizing infection of skin and soft tissues caused by the fresh-water mycobacterium, Mycobacterium ulcerans. While it is rarely fatal, it can profoundly debilitate those it affects, resulting in extreme individual morbidity, as well as a profound financial, emotional and social burden for the families and communities affected. This review of Buruli ulcer details the history, pathogenesis, diagnosis and management of this neglected tropical disease.

Keywords: Buruli ulcer, Bairnsdale ulcer, Daintree ulcer, Mycobacterium ulcerans, tropical diseases, infectious diseases. Read more